Work

The Antioxidant Effect of Palm Fruit Carotene on Skin Lipid Peroxidation in Guinea Pigs as Estimated by Chemiluminescence-HPLC Method.

Year: 1994

Type: article

Abstract: To study the antioxidant effect of palm fruit carotene on skin lipid peroxidation, the guinea pigs were orally fed ad libitum palm fruit carotene, beta-carotene, or vehicle emulsions, in which carotene (0.05%, w/w) was suspended in drinking water. After treatment of carotene for 12 weeks, animals were exposed to ultraviolet ray (UV), and squalene monohydroperoxide (SqOOH)/squalene (Sq) ratios in the skin lipid were analyzed using the chemiluminescence-HPLC method. Carotene accumulation was found in the skin of guinea pigs that were orally administered palm fruit carotene or beta-carotene. After UV irradiation, especially immediately after, the rise in the SqOOH/Sq ratio was effectively suppressed in both carotene-drinking groups in contrast with the control (carotene-untreated) group. An inverse correlation between the carotene content and the SqOOH/Sq ratio in the skin was also observed. The results suggested that palm fruit carotene intake prevents skin lipid peroxidation caused by UV irradiation.

Source: Journal of Nutritional Science and Vitaminology

DOI: 10.3177/jnsv.40.315

Authors: Keita SOMEYA, Yuka TOTSUKA, Michiaki MURAKOSHI, Hirokazu KITANO, Teruo MIYAZAWA

Institutions: Lion Corporation (Japan), Tohoku University

Language: English

Topic: Antioxidant Activity and Oxidative Stress

Subfield: Biochemistry (medical)

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

OpenAlex ID: W2057377874

FWCI: 0.659

Cites: 13

Cited by: 20

Related to: 10