Postprandial Reactive Hypoglycemia in an Oldest-old Patient Effectively Treated with Low-dose Acarbose
Year: 2006
Type: article
Study design: Case Report
Abstract: We recently encountered a 96-year-old Japanese woman who suffered from frequent hypoglycemia. Endocrinological and imaging data eliminated the possibility of insulinoma, whereas oral glucose tolerance testing revealed impaired glucose tolerance and subsequent reactive hypoglycemia. The patterns between insulin or C-peptide secretions and glucose excursions demonstrated that the discrepancy occurred in the late postprandial stage. Administration of small doses of alpha-glucosidase inhibitor (alpha-GI) dramatically inhibited the rapid rise and subsequent precipitous fall of plasma glucose. Reactive hypoglycemia may be one of the important cause of hypoglycemia in the elderly, and alpha-GI could effectively and safely prevent such hypoglycemic attacks in those patients.
Source: Endocrine Journal
Authors: Yoshiaki TAMURA, Atsushi ARAKI, Yuko CHIBA, Toshiyuki HORIUCHI, Seijiro MORI, Takayuki HOSOI
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2057486874