Work

Using a Mathematical Model to Evaluate the Efficacy of TB Control Measures

Year: 1997

Type: review

Abstract: We evaluated the efficacy of recommended tuberculosis (TB) infection control measures by using a deterministic mathematical model for airborne contagion. We examined the percentage of purified protein derivative conversions under various exposure conditions, environmental controlstrategies, and respiratory protective devices. We conclude that environmental control cannot eliminate the risk for TB transmission during high-risk procedures; respiratory protective devices, and particularly high-efficiency particulate air masks, may provide nearly complete protection if used with air filtration or ultraviolet irradiation. Nevertheless, the efficiency of these control measures decreases as the infectivity of the source case increases. Therefore, administrative control measures (e.g., indentifying and isolating patients with infectious TB) are the most effective because they substantially reduce the rate of infection.

Source: Emerging infectious diseases

DOI: 10.3201/eid0303.970310

Authors: Laura Gammaitoni, Maria Clara Nucci

Institution: University of Perugia

Language: English

Topic: Infection Control and Ventilation

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Università degli Studi di Perugia