Hematopoietic Stem Cell Transplantation for Multiple Myeloma: Guidelines from the American Society for Blood and Marrow Transplantation
Year: 2015
Type: review
Abstract: Therapeutic strategies for multiple myeloma (MM) have changed dramatically over the past decade. Thus, the role of hematopoietic stem cell transplantation (HCT) must be considered in the context of this evolution. In this evidence-based review, we have critically analyzed the data from the most recent clinical trials to better understand how to incorporate HCT and when HCT is indicated. We have provided our recommendations based on strength of evidence with the knowledge that ongoing clinical trials make this a dynamic field. Within this document, we discuss the decision to proceed with autologous HCT, factors to consider before proceeding to HCT, the role of tandem autologous HCT, post-HCT maintenance therapy, and the role of allogeneic HCT for patients with MM.
Authors: Nina Shah, Natalie Callander, Siddhartha Ganguly, Zartash Gul, Mehdi Hamadani, Luciano Costa, Salyka Sengsayadeth, Muneer Abidi, Parameswaran Hari, Mohamad Mohty, Yi-Bin Chen, John Koreth, Heather Landau, Hillard Lazarus, Helen Leather, Navneet Majhail, Rajneesh Nath, Keren Osman, Miguel-Angel Perales, Jeffrey Schriber, Paul Shaughnessy, David Vesole, Ravi Vij, John Wingard, Sergio Giralt, Bipin N. Savani
Institutions: The University of Texas MD Anderson Cancer Center, University of Wisconsin–Madison, University of Kansas Medical Center, University of Kentucky, Medical College of Wisconsin, University of Alabama at Birmingham, Vanderbilt University Medical Center, Spectrum Health, Corewell Health Blodgett Hospital, Inserm, Assistance Publique – Hôpitaux de Paris, Hôpital Saint-Antoine, Université Pierre-et-Marie-Curie, Massachusetts General Hospital, Dana-Farber Cancer Institute, Memorial Sloan Kettering Cancer Center, Case Western Reserve University, Cleveland Clinic, University of Massachusetts Chan Medical School, Icahn School of Medicine at Mount Sinai, Hackensack University Medical Center, Washington University in St. Louis, University of Florida Health, University of Florida
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
Funder: National Cancer Institute
Award: Cancer Center Support Grant
OpenAlex ID: W2058038339