Work

Mapping of polypeptides encoded by the Epstein-Barr virus genome in productive infection.

Year: 1982

Type: article

Abstract: Over 30 viral-specified polypeptides are translated in vitro from RNA of cells productively infected with Epstein-Barr virus (EBV). The polypeptides map to sites in EBV DNA by hybrid selection. Almost all of the polypeptides are reactive with EBV immune human serum. Several of the polypeptides are part of the early antigen complex. Two others are likely to be major structural components of the virus. Genes encoding persistent early and late polypeptides are intermixed through most of the EBV genome.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.79.18.5698

Authors: M Hummel, E Kieff

Language: English

Topic: Viral-associated cancers and disorders

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: U.S. Public Health Service

OpenAlex ID: W2058337779

FWCI: 7.362

Cites: 36

Cited by: 75

Related to: 10