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‘Pathway drug cocktail’: targeting Ras signaling based on structural pathways

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Year: 2013
Type: review
Source: Trends in Molecular Medicine
DOI: 10.1016/j.molmed.2013.07.009
Authors: Ruth Nussinov, Chung-Jung Tsai, Carla Mattos
Institutions: Tel Aviv University, National Cancer Institute, Center for Cancer Research, Northeastern University
Language: English

Topic: Protein Kinase Regulation and GTPase Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, U.S. Public Health Service, National Cancer Institute
Awards: G3112995819, G3116884094, G3503792436, G386607036, G4585269469, Mechanism of intrinsic hydrolysis in Ras and the effect of Raf on oncogenic mutan, G9000208986
OpenAlex ID: W2058481347
FWCI: 0.923
Cites: 72
Cited by: 61
Related to: 10
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