Work

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

Year: 2011

Type: review

Source: Nature Reviews Drug Discovery

DOI: 10.1038/nrd3428

Authors: Shankar Balasubramanian, Laurence H. Hurley, Stephen Neidle

Institutions: University of Cambridge, University of Arizona, BIO5 Institute, University of Arizona Cancer Center, University of London, Cancer Research UK, UCL School of Pharmacy

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Cancer Research UK, Biotechnology and Biological Sciences Research Council, National Cancer Institute, National Institute of General Medical Sciences

Awards: G2273925550, Analysis of Quadruplex Function in the Genome, G-quadruplexes formed in human oncogene promoters and their drug complexes, G4470602312, Establishing a molecular system for drug targeting of transcriptional control, Specialized Program Research Excellence (SPORE) in Gastrointestinal Cancer

OpenAlex ID: W2059306569

FWCI: 9.731

Cites: 144

Cited by: 1,728

Related to: 10