Work

On the Theory of Solute Solubility in Mixed Solvents

Year: 2008

Type: article

Abstract: A series of equations are developed for the study of the effects of cosolvents on the solubility of a solute in mixed solutions where the solute displays a finite solubility. The equations differ depending on the scale used for the solute (and cosolvent) concentrations. The expressions use Kirkwood-Buff integrals to relate the changes in solubility to changes in the local solution composition around the solute and can be applied to study any type of ternary system including electrolyte cosolvents. The expressions provided here differ from previous approaches because of the use of a semi-open ensemble and the extension to finite solute solubilities.

Source: The Journal of Physical Chemistry B

DOI: 10.1021/jp712179w

Authors: Paul E. Smith, Robert M. Mazo

Institutions: University of Oregon, Kansas State University

Language: English

Topic: Crystallization and Solubility Studies

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Accurate Simulations of Peptide Aggregation