The LRC haplotype project: a resource for killer immunoglobulin‐like receptor‐linked association studies
Year: 2006
Type: article
Abstract: There is increasing evidence for epistatic interactions between gene products (e.g. KIR) encoded within the Leukocyte Receptor Complex (LRC) with those (e.g. HLA) of the Major Histocompatibility Complex (MHC), resulting in susceptibility to disease. Identification of such associations at the DNA level requires comprehensive knowledge of the genetic variation and haplotype structure of the underlying loci. The LRC haplotype project aims to provide this knowledge by sequencing common LRC haplotypes.
Source: Tissue Antigens
Authors: R. Horton, P. Coggill, M. M. Miretti, J. G. Sambrook, J. A. Traherne, R. Ward, S. Sims, S. Palmer, H. Sehra, J. Harrow, J. Rogers, M. Carrington, J. Trowsdale, S. Beck
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2059809438