Quest for the descent of the Escherichia coli outbreak strain TY2482 – out of Germany?
Year: 2011
Type: preprint
Abstract: The recent outbreak of the Escherichia coli infection in north Germany reportedly has killed 35 people and sickened about 4000. Infections were reported in 2001 and 2002 in Germany and Central Africa respectively. In order to dissect all possible connections among the three infection/outbreak strains and to extract the most virulent genes responsible for the augmented pathogenicity of the present German strain (2011), whole genome sequence data of the two isolates (E. coli TY_2482 & LB226692) were analyzed. We report that the German outbreak strain isolated in 2011 is a seasoned clone of the 2002 isolate sequenced from Central Africa (55989) and perhaps a direct descendent of the German EAEC strain reported in 2001 infection cases.
Source: Nature Precedings
Institutions: University of Hyderabad, Freie Universität Berlin
Language: English
Subfield: Endocrinology
Domain: Life Sciences
Open Access status: diamond
Funder: Deutsche Forschungsgemeinschaft
OpenAlex ID: W2059887160