Work

In Vitro and in Vivo Studies of Single-Walled Carbon Nanohorns with Encapsulated Metallofullerenes and Exohedrally Functionalized Quantum Dots

Year: 2010

Type: article

Abstract: Single-walled carbon nanohorns (SWNHs) are new carbonaceous materials. In this paper, we report the first successful preparation of SWNHs encapsulating trimetallic nitride template endohedral metallofullerenes (TNT-EMFs). The resultant materials were functionalized by a high-speed vibration milling method and conjugated with CdSe/ZnS quantum dots (QDs). The successful encapsulation of TNT-EMFs and external functionalization with QDs provide a dual diagnostic platform for in vitro and in vivo biomedical applications of these new carbonaceous materials.

Source: Nano Letters

DOI: 10.1021/nl1008635

Authors: Jianfei Zhang, Jiechao Ge, Michael D. Shultz, Eunna Chung, Gurpreet Singh, Chunying Shu, Panos P. Fatouros, Scott C. Henderson, Frank D. Corwin, David B. Geohegan, Alex A. Puretzky, Christopher M. Rouleau, Karren More, Christopher Rylander, Marissa Nichole Rylander, Harry W. Gibson, Harry C. Dorn

Institutions: Virginia Tech, Virginia Commonwealth University, Oak Ridge National Laboratory, Center for Nanophase Materials Sciences

Language: English

Topic: Fullerene Chemistry and Applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke, Division of Materials Sciences and Engineering

Awards: Trimetallic Nitride Templated Endohedral Metallofullerenes as Dual Imaging and Mu, Metallofullerene Nanoplatform for Imaging & Treatment, G214517448, G25200180, VCU Neuroscience Center Core Grant, G406528335

OpenAlex ID: W2059891905

FWCI: 3.642

Cites: 36

Cited by: 58

Related to: 10