Toward understanding the genetics of regulatory T cells in ovarian cancer
Year: 2013
Type: article
Abstract: Tumor-infiltrating regulatory T cells (Tregs) promote immune evasion and are associated with poor disease outcome in patients affected by various malignancies. We have recently demonstrated that several, inherited single nucleotide polymorphisms affecting Treg-related genes influence the survival of ovarian cancer patients, providing novel insights into possible mechanisms of immune escape.
Source: OncoImmunology
DOI: 10.4161/onci.24535
Institution: Mayo Clinic
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,913
Funder: National Cancer Institute
OpenAlex ID: W2059996393