Work

Pemphigoid and pemphigus antigens in cultured epidermal cells

Year: 1978

Type: article

Abstract: Fractions of IgG from sera of patients with pemphigoid and pemphigus added to monolayer cultures of mouse epidermal cells resulted in a sparse distribution of cells. Direct immunofluorescence studies of these monolayers revealed epidermal cell surface antigens reacting with pemphigoid and pemphigus antibodies. We suggest that these antibodies may bind to epidermal cell surface antigenic molecules which are important in maintaining epidermal cell adhesion in culture.

Source: British Journal of Dermatology

DOI: 10.1111/j.1365-2133.1978.tb03581.x

Authors: LUIS A. DIAZ, CYNTHIA L. MARCELO

Institutions: University of Michigan, Michigan Medicine

Language: English

Topic: Autoimmune Bullous Skin Diseases

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institutes of Health