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Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report

Year: 2012

Type: article

Abstract: This case report exhibits a rare biliary tumor within the liver of a 53-year-old Caucasian woman. This exophytic, multicystic, 6.5 × 5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofibroma. This is the seventh case described in the literature. Multiple foci of high-grade dysplasia/carcinoma in situ were found with a microscopic focus of invasive carcinoma in review of the pathology, making this only the second case reporting malignant transformation. It is presented to illustrate the premalignant potential in a biliary epithelial tumor currently categorized as benign.

Source: Case Reports in Hepatology

DOI: 10.1155/2012/793963

Authors: N. Thao T. Nguyen, Theresa R. Harring, Laurie Holley, John A. Goss, Christine A. O’Mahony

Institutions: Baylor College of Medicine, Baylor St. Luke's Medical Center

Language: English

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $790