Work

Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

Year: 2013

Type: article

Abstract: BACKGROUND: Evidence for non-steroidal anti-inflammatory drugs (NSAIDs) preventing head and neck cancer (HNC) is inconclusive; however, there is some suggestion that aspirin may exert a protective effect. METHODS: Using data from the United States National Cancer Institute Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we examined the association between aspirin and ibuprofen use and HNC. RESULTS: Regular aspirin use was associated with a significant 22% reduction in HNC risk. No association was observed with regular ibuprofen use. CONCLUSION: Aspirin may have potential as a chemopreventive agent for HNC, but further investigation is warranted.

Source: British Journal of Cancer

DOI: 10.1038/bjc.2013.73

Authors: J C Wilson, L J Murray, C M Hughes, A Black, L A Anderson

Institutions: Queen's University Belfast, Royal Victoria Hospital, National Institutes of Health, National Cancer Institute

Language: English

Topic: Inflammatory mediators and NSAID effects

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,190