Estimation and comparison of levels of salivary nitric oxide in patients with oral lichen planus and controls.
Year: 2013
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Normal salivary function is considered to be critical for the maintenance of healthy oral mucosa. Oral fluids provide an easily available, non-invasive medium for the diagnosis of wide range of diseases and clinical situations. The objective of this study was to estimate and compare salivary nitric oxide levels in patients with oral lichen planus and healthy individuals. METHODS: Saliva was collected by spitting method. Unstimulated whole saliva thus collected was refrigerated at 4°C, and processed within 24 h for the estimation of nitric oxide levels which was done using Griess reaction. The results were analyzed using Student's "t" test. RESULTS: There was statistically significant difference in the levels of salivary nitric oxide between the study and control groups. CONCLUSIONS: The present study clearly indicates a significant increase in salivary nitric oxide levels in oral lichen planus patients as compared to controls.
Source: Europe PMC (PubMed Central)
Authors: Sapna Panjwani, Anjana Bagewadi, Vaishali Keluskar, Rohit Malik, Shalu Rai, Deepankar Misra
Language: English
Subfield: General Dentistry
Field: Dentistry
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2060476373