Work

Nanoscale Flexibility Parameters of Alzheimer Amyloid Fibrils Determined by Electron Cryo‐Microscopy

Year: 2010

Type: article

Abstract: Versatile nanomaterial: Unusually high nanoscale flexibility was displayed by amyloid fibils in electron microscopy studies (see picture). This finding is relevant for understanding amyloid pathogenicity and for potential biotechnological applications.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200904781

Authors: Carsten Sachse, Nikolaus Grigorieff, Marcus Fändrich

Institutions: MRC Laboratory of Molecular Biology, Howard Hughes Medical Institute, Brandeis University, Max Planck Research Unit for Enzymology of Protein Folding, Martin Luther University Halle-Wittenberg

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

Open Access status: bronze

Funders: Howard Hughes Medical Institute, National Institute of General Medical Sciences

Awards: Atomic Resolution in Biological Electron Microscopy, G4136753765