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Synthesis and Anticancer Activity of Simplified Indenoisoquinoline Topoisomerase I Inhibitors Lacking Substituents on the Aromatic Rings

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Year: 2004
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm040025z
Authors: Muthukaman Nagarajan, Andrew Morrell, Brian C. Fort, Marintha Rae Meckley, Smitha Antony, Glenda Kohlhagen, Yves Pommier, Mark Cushman
Institutions: Purdue University West Lafayette, National Cancer Institute, Center for Cancer Research
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute
Awards: G256744984, G3029148, Novel Topoisomerase I Inhibitors, OPERATIONS &TECHNICAL SUPPORT, Training in Drug and Carcinogen-DNA Interactions, G8567291711
OpenAlex ID: W2060916958
FWCI: 2.186
Cites: 17
Cited by: 131
Related to: 10
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