Work

Illuminating the landscape of host–pathogen interactions with the bacterium Listeria monocytogenes

Year: 2011

Type: review

Abstract: Listeria monocytogenes has, in 25 y, become a model in infection biology. Through the analysis of both its saprophytic life and infectious process, new concepts in microbiology, cell biology, and pathogenesis have been discovered. This review will update our knowledge on this intracellular pathogen and highlight the most recent breakthroughs. Promising areas of investigation such as the increasingly recognized relevance for the infectious process, of RNA-mediated regulations in the bacterium, and the role of bacterially controlled posttranslational and epigenetic modifications in the host will also be discussed.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.1112371108

Author: Pascale Cossart

Institutions: Inserm, Institut Pasteur, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Biology of Infection, Institut National de la Recherche Agronomique

Language: English

Topic: Listeria monocytogenes in Food Safety

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Howard Hughes Medical Institute