Work

Antioxidant Activity of Saponins Isolated from Ivy: α-Hederin, Hederasaponin-C, Hederacolchiside-E and Hederacolchiside-F

Year: 2004

Type: article

Abstract: The antioxidant activities of alpha-hederin and hederasaponin-C from Hedera helix, and hederacolchisides-E and -F from Hedera colchica were investigated, in this study. The antioxidant properties of the saponins were evaluated using different antioxidant tests: 1,1-di-phenyl-2-picryl-hydrazyl (DPPH.) free radical scavenging, total antioxidant activity, reducing power, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities. Alpha-hederin, hederasaponin-C, as well as hederacolchisides-E and -F exhibited a strong total antioxidant activity. At the concentration of 75 pg/mL, these saponins showed 94, 86, 88 and 75% inhibition on lipid peroxidation of linoleic acid emulsion,respectively. These various antioxidant activities were compared with model antioxidants such as a-tocopherol, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT).

Source: Planta Medica

DOI: 10.1055/s-2004-827158

Authors: İlhami Gülçin, Vakhtang Mshvildadze, Akçahan Gepdiremen, Riad Elias

Institutions: Atatürk University, Georgian National Academy of Sciences, Aix-Marseille Université

Language: English

Topic: Natural product bioactivities and synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2061214188

FWCI: 1.214

Cites:

Cited by: 178

Related to: 10