Work

Comparison of coherent and spontaneous Raman microspectroscopies for noninvasive detection of single bacterial endospores

Year: 2007

Type: article

Abstract: Single bacterial spores were analyzed by using nonlinear Raman microspectroscopy based on coherent anti-Stokes Raman scattering (CARS). The Raman spectra were retrieved from CARS spectra and found to be in excellent agreement with conventionally collected Raman spectra. The phase retrieval method based on maximum entropy model revealed significant robustness to external noise. The direct comparison of signal amplitudes exhibited a factor of 100 stronger CARS signal, as compared with the Raman signal.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.0702107104

Authors: Georgi I. Petrov, Rajan Arora, Vladislav V. Yakovlev, Xi Wang, Alexei V. Sokolov, Marlan O. Scully

Institutions: University of Wisconsin System, Texas A&M University, Princeton University

Language: English

Topic: Spectroscopy Techniques in Biomedical and Chemical Research

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green