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Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen

Year: 1981

Type: article

Abstract: Some human B-lymphoblastoid cell lines are shown to express at least two types of Ia-like antigens. One antigen is defined by alloantisera to HLA-DR, and the other antigen is defined by alloantisera and a monoclonal antibody to the specificities DC1, MT1 (MB1), and LB12, which are in linkage disequilibrium with HLA-DR. The subunits of the DC1 molecule differ from those of the DR molecule. The light chains of both molecules are structurally polymorphic.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.78.7.4566

Authors: Deborah A. Shackelford, Dean L. Mann, Jon J. van Rood, G. B. Ferrara, Jack L. Strominger

Institutions: Harvard University, National Institutes of Health, National Cancer Institute, Leiden University Medical Center

Language: English

Topic: vaccines and immunoinformatics approaches

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2061622277

FWCI: 24.52

Cites: 24

Cited by: 202

Related to: 10