Work

Cooperative Interactions Between Pairs of Homologous Chromatids During Meiosis in Saccharomyces cerevisiae

Year: 2008

Type: article

Abstract: We report a novel instance of negative interference during Saccharomyces cerevisiae meiosis, where Cre-mediated recombination between pairs of allelic loxP sites is more frequent than expected. We suggest that endogenous crossover recombination mediates cooperative pairing interactions between all four chromatids of a meiotic bivalent.

Source: Genetics

DOI: 10.1534/genetics.108.088567

Authors: Joshua Chang Mell, Kelly Komachi, Owen Hughes, Sean Burgess

Institution: University of California, Davis

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Environmental Health Sciences

Awards: Homologous Chromosome Pairing in Meiosis, ANEUGEN SCREENING IN OPTIMIZED YEAST STRAINS, G3798075608, G6973184780