Work

Intra-Arterial Delivery of Cell Therapies for Stroke

Year: 2011

Type: review

Abstract: Cell therapy is a novel investigational approach to enhance stroke recovery. Intra-arterial (IA) delivery has the potential advantage of selectively targeting cell therapies to the ischemic brain tissue. Over the past 10 years, IA cell delivery has been under investigation in patients with cardiac and peripheral vascular disease, and these studies have reported promising results. This article reviews the trial methodology and procedural details of these studies and discusses the rationale and challenges in designing IA cell therapy trials for ischemic stroke.

Source: Stem Cells and Development

DOI: 10.1089/scd.2011.0612

Authors: Vivek Misra, Aditya Lal, Ramy El Khoury, Peng R. Chen, Sean I. Savitz

Institution: The University of Texas Health Science Center at Houston

Language: English

Topic: Mesenchymal stem cell research

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Center for Research Resources