Work

Meta-analysis of cancer incidence in children born after assisted reproductive technologies

Year: 2005

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: A meta-analysis was performed on 11 cohort studies of Assisted Reproductive Technologies (ART) and subsequent childhood cancer, published up to February 2005, which reported comparable, nonoverlapping data, and then restricted to eight studies which presented a similar research design. The overall Standardised Incidence Ratio was 1.33 (95% CI 0.62-2.85), and 0.77 (95% CI 0.41-1.42) when the analysis was restricted to eight studies. No evidence of publication bias was observed for the overall analysis. The data are consistent with a lack of increase in risk of childhood cancer, though the amount of data on ART and cancer is still limited; larger multicentric studies as well as a pooled analysis on the available data are warranted.

Source: British Journal of Cancer

DOI: 10.1038/sj.bjc.6602838

Authors: S Raimondi, P Pedotti, E Taioli

Institution: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Language: English

Topic: Assisted Reproductive Technology and Twin Pregnancy

Subfield: Pediatrics, Perinatology and Child Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $5,190