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Inside Back Cover: Single‐Molecule Mechanochemical Sensing Using DNA Origami Nanostructures (Angew. Chem. Int. Ed. 31/2014)

Year: 2014

Type: article

Abstract: DNA origami nanotiles have been used as novel multiplex mechanochemical sensors. In their Communication on page 8137 ff., M. Endo, H. Sugiyama, H. Mao et al. show that the binding of specific target molecules to the sensor unlocks the interconnected tiles, and the global topology of the DNA nanostructure rearranges. This process is monitored as mechanochemical signals in real time using optical tweezers.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201406158

Authors: Deepak Koirala, Prakash Shrestha, Tomoko Emura, Kumi Hidaka, Shankar Mandal, Masayuki Endo, Hiroshi Sugiyama, Hanbin Mao

Institutions: Kent State University, Kyoto University, Japan Science and Technology Agency

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2062391886

FWCI: 0.244

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Cited by: 2

Related to: 10