Work

Aza-peptidyl Michael Acceptors. A New Class of Potent and Selective Inhibitors of Asparaginyl Endopeptidases (Legumains) from Evolutionarily Diverse Pathogens

Year: 2008

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/jm701311r

Authors: Marion G. Götz, Karen Ellis James, Elizabeth Hansell, Jan Dvořák, Amritha Seshaadri, Daniel Sojka, Petr Kopáček, James H. McKerrow, Conor R. Caffrey, James C. Powers

Institutions: Georgia Institute of Technology, University of California, San Francisco, Institute of Parasitology, Czech Academy of Sciences, Biology Centre

Language: English

Topic: Protease and Inhibitor Mechanisms

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: Grantová Agentura České Republiky, Directorate for Biological Sciences, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: SERINE AND CYSTEINE PROTEASES IN T LYMPHOCYTE KILLING, CASPASE INHIBITORS, Host Protein Degradation by Schistosome Parasites

OpenAlex ID: W2062427408

FWCI: 1.333

Cites: 53

Cited by: 54

Related to: 10