Work

Catalytic mechanism of KDO8P synthase. Pre-steady-state kinetic analysis using rapid chemical quench flow methods

Year: 1997

Type: article

Abstract: The catalytic mechanism of 3-deoxy-d-manno-2-octulosonate-8-phosphate (Kdo8P) synthase from Escherichia coli was investigated under pre-steady-state conditions using rapid chemical quench flow methods. The results suggest the formation of acyclic bisphosphate 1 as a reaction intermediate.

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/s0960-894x(97)10021-x

Authors: Po-Huang Liang, Amnon Kohen, Timor Baasov, Karen S. Anderson

Institutions: Yale University, Technion – Israel Institute of Technology

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,880

OpenAlex ID: W2063439236

FWCI: 1.545

Cites: 23

Cited by: 18

Related to: 10