Work

Bone-Immune Cell Crosstalk: Bone Diseases

Year: 2015

Type: article

Abstract: Bone diseases are associated with great morbidity; thus, the understanding of the mechanisms leading to their development represents a great challenge to improve bone health. Recent reports suggest that a large number of molecules produced by immune cells affect bone cell activity. However, the mechanisms are incompletely understood. This review aims to shed new lights into the mechanisms of bone diseases involving immune cells. In particular, we focused our attention on the major pathogenic mechanism underlying periodontal disease, psoriatic arthritis, postmenopausal osteoporosis, glucocorticoid-induced osteoporosis, metastatic solid tumors, and multiple myeloma.

Source: Journal of Immunology Research

DOI: 10.1155/2015/108451

Authors: Giorgio Mori, Patrizia D’Amelio, Roberta Faccio, Giacomina Brunetti

Institutions: University of Foggia, University of Turin, Washington University in St. Louis, University of Bari Aldo Moro

Language: English

Topic: Bone Metabolism and Diseases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,830