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Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6–independent mechanism

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Year: 2002
Type: article
Source: Blood
DOI: 10.1182/blood-2002-03-0940
Authors: Yun Dai, Terry H. Landowski, Steven T. Rosen, Paul Dent, Steven Grant
Institutions: University of Arizona, Virginia Commonwealth University, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Virginia Commonwealth University Medical Center
Language: English

Topic: Multiple Myeloma Research and Treatments
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases
Awards: G1191033322, G1685919197, POTENTIATION OF TAXANE ACTIVITY BY MEK/MAPK INHIBITORS, G2585495816, Carcinoma cell radiosensitization by MAPK inhibition, Promotion of Nucleoside Analog Induced Apoptosis by HDIs, COMPLEMENT AND THE COMPLICATIONS OF DIABETES, G890863337
OpenAlex ID: W2063631973
FWCI: 3.9
Cites: 58
Cited by: 94
Related to: 10
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