Work

SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age

Year: 2014

Type: article

Source: Nature Communications

DOI: 10.1038/ncomms6011

Authors: Michael Van Meter, Mehr Kashyap, Sarallah Rezazadeh, Anthony J. Geneva, Timothy D. Morello, Andrei Seluanov, Vera Gorbunova

Institution: University of Rochester

Language: English

Topic: Chromosomal and Genetic Variations

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Ellison Medical Foundation, National Institutes of Health, National Institute on Aging

Awards: Molecular mechanisms which regulate SIRT6 activity and their relevance to aging, Comparative Analysis of DNA Break Repair in Short- and Long-Lived Rodent Species, Regulation of genome stability by SITR6, The role of SIRT6 posttranslational modifications in aging and genome stability, Comparative genomics of longevity and Alzheimer's disease

OpenAlex ID: W2064802388

FWCI: 15

Cites: 57

Cited by: 455

Related to: 10