Work

Response: More on disease anticipation in familial MPN

Year: 2008

Type: article

Abstract: median 38 years, range 23-57; P Ͻ .001).In addition, we studied the telomere length using flow cytometric analysis 2 in 10 families with 2-generation pairs.Wilcoxon matched-pair test showed a significantly shortened telomere length in offspring compared with parents (P ϭ .005). Figure 1 shows telomere shortening between the 2 generations and the variation of the length between members of the same family.In conclusion, taking into account for the familial links, our analysis provides evidence of disease anticipation in familial MPN.

Source: Blood

DOI: 10.1182/blood-2008-07-161620

Authors: Ola Landgren, Lynn R. Goldin, Sigurdur Y. Kristinsson, Elin A. Helgadottir, Jan Samuelsson, Magnus Bjorkholm

Language: English

Topic: Myeloproliferative Neoplasms: Diagnosis and Treatment

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2064936044

FWCI:

Cites: 9

Cited by: 1

Related to: 10