Work

Molecular Surveillance for Multidrug-ResistantPlasmodium falciparum, Cambodia

Year: 2008

Type: article

Study design: Observational Study

Abstract: We conducted surveillance for multidrug-resistant Plasmodium falciparum in Cambodia during 2004-2006 by assessing molecular changes in pfmdr1. The high prevalence of isolates with multiple pfmdr1 copies found in western Cambodia near the Thai border, where artesunate-mefloquine therapy failures occur, contrasts with isolates from eastern Cambodia, where this combination therapy remains highly effective.

Source: Emerging infectious diseases

DOI: 10.3201/eid1410.080080

Authors: Naman K. Shah, Alisa P. Alker, Rithy Sem, Agustina Ika Susanti, Sinuon Muth, Jason D. Maguire, Socheat Duong, Frederic Ariey, Steven R. Meshnick, Chansuda Wongsrichanalai

Institutions: University of North Carolina at Chapel Hill, Institut Pasteur du Cambodge, Cambodia National Malaria Center

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: U.S. Department of Defense, International Atomic Energy Agency, National Institutes of Health, U.S. Navy, Fogarty International Center, Naval Medical Research Center

Awards: G7069906608, G7249931220, Research Training for Cambodian Scientists in Effective*

OpenAlex ID: W2065068410

FWCI: 3.619

Cites: 11

Cited by: 34

Related to: 10