Work

Structure of yeast phenylalanine transfer RNA at 2.5 A resolution.

Year: 1975

Type: article

Abstract: The x-ray analysis of the monoclinic form of yeast tRNAPhe has been taken to a resolution of 2.5 A by the method of isomorphous replacement. The model proposed at 3 A has been confirmed and extended to reveal additional features of the tertiary structure and of the stereochemistry. An extensive hydrogen bonding network is described involving specific interactions between bases and the ribose-phosphate backbone. The structure of a G-U base pair has been solved.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.72.11.4414

Authors: J E Ladner, A Jack, J D Robertus, R S Brown, D Rhodes, B F Clark, A Klug

Institutions: Medical Research Council, MRC Laboratory of Molecular Biology

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2065458612

FWCI: 8.944

Cites: 17

Cited by: 282

Related to: 9