Work

Collagen Synthesis: A Disulfide-Linked Collagen Precursor in Chick Bone

Year: 1973

Type: article

Abstract: Chick calvaria labeled in vitro contain a triple-stranded collagen precursor that contains two pro alpha1 and one pro alpha2 chains. All chains contain cystine and are linked by S-S bonds. Ultracentrifugal analysis was used to measure the relative size of the disulfide-linked units. It is proposed that the S-S links help to determine the correct alignment of the triple-stranded structure.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.70.10.2993

Authors: L. I. Fessler, R. E. Burgeson, N. P. Morris, J. H. Fessler

Institution: University of California, Los Angeles

Language: English

Topic: Collagen: Extraction and Characterization

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

Open Access status: green

Funders: American Heart Association, U.S. Public Health Service

OpenAlex ID: W2065757741

FWCI: 7.061

Cites: 11

Cited by: 40

Related to: 10