Work

Degradable, Surfactant‐Free, Monodisperse Polymer‐Encapsulated Emulsions as Anticancer Drug Carriers

Year: 2009

Type: article

Abstract: Anticancer emulsions: Degradable, surfactant- free, micrometer- to sub-micrometer-sized polymer-encapsulated emulsions loaded with lipophilic drugs (doxorubicin and 5-fluorouracil) are prepared. In vitro drug-release studies demonstrate controlled release under redox conditions and incubation with human colorectal cancer cells triggers cell death with greater efficiency (≈106 fold) than the free drug.

Source: Advanced Materials

DOI: 10.1002/adma.200802475

Authors: Sri Sivakumar, Vipul Bansal, Christina Cortez, Siow‐Feng Chong, Alexander N. Zelikin, Frank Caruso

Institution: The University of Melbourne

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green