Work

Hotspots of homologous recombination in the human genome: not all homologous sequences are equal.

Year: 2004

Type: review

Abstract: Homologous recombination between alleles or non-allelic paralogous sequences does not occur uniformly but is concentrated in 'hotspots' with high recombination rates. Recent studies of these hotspots show that they do not share common sequence motifs, but they do have other features in common.

Source: Genome biology

DOI: 10.1186/gb-2004-5-10-242

Author: James R Lupski

Institutions: Baylor College of Medicine, Wellcome Sanger Institute

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $5,490

OpenAlex ID: W2066012419

FWCI: 0.584

Cites: 37

Cited by: 71

Related to: 10