Work

18 F-FDG Uptake in Lung, Breast, and Colon Cancers: Molecular Biology Correlates and Disease Characterization

Year: 2009

Type: review

Abstract: It is hoped that in the not too distant future, noninvasive imaging-based molecular interrogation and characterization of tumors can improve our fundamental understanding of the dynamic biologic behavior of cancer. For example, the new dimension of diagnostic information that is provided by (18)F-FDG PET has led to improved clinical decision making and management changes in a substantial number of patients with cancer. In this context, the aim of this review is to bring together and summarize the current data on the correlation between the underlying molecular biology and the clinical observations of tumor (18)F-FDG accumulation in 3 major human cancers: lung, breast, and colon.

Source: Journal of Nuclear Medicine

DOI: 10.2967/jnumed.108.054098

Authors: Hossein Jadvar, Abass Alavi, Sanjiv S. Gambhir

Institutions: University of Southern California, University of Pennsylvania, Stanford Medicine, Stanford University

Language: English

Topic: Medical Imaging Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, U.S. Public Health Service, National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering