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The IL-15 superagonist ALT-803 enhances anti-CD20 antibody-directed NK cell ADCC and in vivo clearance of B cell lymphomas

Year: 2014
Type: conference-abstract
Abstract: Meeting abstracts NK cells are innate lymphoid cells that mediate potent anti-tumor responses against B cell malignancies in conjunction with anti-CD20 mAbs. ALT-803 is a superagonist IL-15 and dimeric IL-15Rα-IgG-Fc fusion protein that effectively trans-presents IL-15 and exhibits prolonged in
DOI: 10.1186/2051-1426-2-s3-p168
Authors: Maximillian Rosario, Bai Liu, Lin Kong, Stephanie E Schneider, Emily K Jeng, Peter R Rhode, Hing C Wong, Todd A Fehniger
Language: English
Subfield: Immunology
Open Access status: gold
Estimated APC paid: $2,490
OpenAlex ID: W2066797203
Cites:
Cited by: 3
Related to: 10