Work

Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects.

Year: 1984

Type: article

Abstract: The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal subjects. LTC4 and LTD4 were shown to be more potent bronchoconstrictors than histamine, with a more sustained action. LTC4 and LTD4 caused wheezing without cough or throat irritation and were shown to act on large and small airways.

Source: Thorax

DOI: 10.1136/thx.39.7.500

Authors: N C Barnes, P J Piper, J F Costello

Institutions: Royal College of Surgeons of England, King's College Hospital

Language: English

Topic: Asthma and respiratory diseases

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: King's College London