29: Addition of Etanercept to Methylprednisolone as Initial Therapy for Acute GVHD Results in High Response Rates and Improved Survival
Year: 2008
Type: article
Abstract: Standard therapy for GVHD, high dose steroids, results in complete responses in only 35% of patients. Because tumor necrosis factor (TNF) is an important effector of GVHD we treated 61 pts with new onset GVHD with methlyprednisolone 2 mg/kg/d plus etanercept, a TNF inhibitor. All pts continued their prophylaxis agent, usually tacrolimus, at therapeutic dosing.
Institution: University of Michigan
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,650
OpenAlex ID: W2067166323