Work

NY-ESO-1 expression in sarcomas

Year: 2012

Type: article

Abstract: NY-ESO-1 (CTAG 1B) is highly expressed in the majority of synovial sarcomas and myxoid/round cell liposarcomas as well as in a subset of melanomas, but only rarely in other mesenchymal tumors. This points to a potential for using NY-ESO-1 in the differential diagnosis of these lesions. Furthermore, promising results have been obtained in clinical trials testing NY-ESO-1-targeted immunotherapy in subsets of melanoma and synovial sarcoma patients.

Source: OncoImmunology

DOI: 10.4161/onci.21059

Authors: Jin-Ping Lai, Avi Z. Rosenberg, Markku M. Miettinen, Chyi-Chia R. Lee

Institutions: National Institutes of Health, National Cancer Institute

Language: English

Topic: Sarcoma Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,913