Work

Organelle size control systems: From cell geometry to organelle‐directed medicine

Year: 2012

Type: review

Abstract: Organelles are reaction vessels containing metabolic pathways. As in a chemical factory, the size of the reaction vessels limits the rate of product formation. Organelle size is tuned to metabolic needs, hence reprogramming organelle size could be a novel therapeutic strategy as well as a new tool for metabolic engineering.

Source: BioEssays

DOI: 10.1002/bies.201200043

Author: Wallace F. Marshall

Institution: University of California, San Francisco

Language: English

Topic: Cellular transport and secretion

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: Exploring Design Principles of Cellular Control Circuits, G4570094121