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Bioassay for SF 86-327, a new antifungal agent

Year: 1986

Type: article

Abstract: A bioassay with Trichophyton mentagrophytes is described for SF 86-327, an allylamine antifungal agent. SF 86-327 serum concentrations were measured by bioassay in 117 serum sampler from five patients receiving 500 mg/day. The peak, trough, and area under the concentration-time curve were determined after the first dose and at steady state. Drug accumulation occurred with prolonged therapy.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.30.4.628

Authors: V L Kan, D K Henderson, J E Bennett

Institution: National Institutes of Health

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2068146834

FWCI: 0.386

Cites: 4

Cited by: 16

Related to: 10