Year: 1956
Type: article
Abstract: The concentration of non-esterified fatty acids (NEFA) in plasma increases after an injection of heparin (1). Apparently a lipase released into the blood (2, 3) hydrolyzes the neutral fat in chylomicrons (4) and promotes both the reduction of turbidity in the plasma and removal of fatty acids to tissues. If the small amounts of NEFA normally pres-ent in blood arise from hydrolysis of circulating triglycerides, the concentration should remain constant or increase to some extent during spon-taneous clearing of alimentary lipemia, depending on relative rates of liberation and removal. This expectation was not supported by the present work. In every case, after a mixed meal, NEFA
DOI: 10.1172/jci103259
Author: Vincent P. Dole
Institution: Rockefeller University
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2068430810