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Complete Genome Sequence of a Tenth Human Polyomavirus

Year: 2012

Type: article

Abstract: Nine polyomavirus (PyV) species are known to productively infect humans. The circular DNA genomes of PyVs are readily detectable using rolling circle amplification (RCA). RCA-based analysis of condyloma specimens from a patient with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome demonstrated the presence of a tenth apparently human-tropic polyomavirus species, which we name HPyV10.

Source: Journal of Virology

DOI: 10.1128/jvi.01690-12

Authors: Christopher B. Buck, Giao Q. Phan, Manish T. Raiji, Philip M. Murphy, David H. McDermott, Alison A. McBride

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Language: English

Topic: Polyomavirus and related diseases

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases