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Porcine Epidemic Diarrhea Virus Replication in Duck Intestinal Cell Line

Year: 2014
Type: article
Abstract: To the Editor: Porcine epidemic diarrhea virus (PEDV) was first detected in pigs in the United States in May 2013 (1).Since then, according to the American Association of Swine Veterinarians (https://www.aasv.org,see link to number of new cases reported), PEDV has spread to 41 states, and as of October 15, 2014, 8,622 confirmed cases of PEDV infection have been reported in swine.PEDV (family Coronaviridae, genus Alphacoronavirus) is an enveloped, positive-sense, single-stranded RNA virus (2).The virus replicates in epithelial cells of small and large intestines and causes highly contagious infection in pigs.The disease is characterized by watery diarrhea, vomiting (leading to subsequent dehydration), and high rates of death, especially in young piglets; thus, outbreaks cause substantial economic losses to the swine industry (1).Variants of the original virulent PEDV have recently been isolated in the United States, making development of a vaccine to protect against this devastating disease even more
Language: English
Open Access status: diamond
OpenAlex ID: W2068707110
FWCI: 3.56
Cites: 6
Cited by: 16
Related to: 10