Work

Killing Kinetics of Caspofungin, Micafungin, and Amphotericin B against Candida guilliermondii

Year: 2006

Type: article

Abstract: Amphotericin B (AMB), micafungin, and caspofungin MICs, minimal fungicidal concentrations, and time-killing curves were determined in the presence and absence of 10% inactivated serum. AMB was the only agent with consistent killing activity (time required to achieve 99.9% of growth reduction was 2.1 to 3.2 h). The presence of serum enhanced caspofungin activity but lowered those of micafungin and AMB.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00524-06

Authors: Emilia Cantón, Javier Pemán, Macrina Sastre, Mónica Romero, Ana Espinel-Ingroff

Institutions: Hospital Universitari i Politècnic La Fe, Virginia Commonwealth University Medical Center

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2068776047

FWCI: 2.929

Cites: 25

Cited by: 37

Related to: 10