Work

C(sp3)18F Bond Formation by Transition‐Metal‐Based [18F]Fluorination

Year: 2014

Type: article

Abstract: Without a trace? Recent advances in aliphatic radiofluorinations enabled by transition metals, specifically cobalt/salen and manganese/salen complexes, have been unveiled. These new approaches operate in a unique way which obviates the need for highly activated substrates for radiolabeling and offers a new synthetic strategy to prepare 18F-labeled radiotracers.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.201407065

Authors: Steven H. Liang, Neil Vasdev

Institutions: Harvard University, Massachusetts General Hospital

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funder: National Institute on Drug Abuse

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