Leptomeningeal dissemination from an ethmoidal sinus adenocarcinoma in cerebrospinal fluid cytology: Figure 1.
Year: 2015
Type: article
Study design: Case Report
Abstract: A 68-year-old man was admitted to hospital because of the presence of neurological symptoms (mainly frontal headache and confusion) and signs of meningeal irritation. According to his medical records, he was an ex-smoker (2 years ago) and he suffered from perennial rhinitis. The patient did not report labor precedents in relation to the exposure to wood, leather or others. After physical examination, a lumbar puncture, computed tomography (CT) scans, and later, a trans-nasal endoscopic biopsy were performed. The patient’s condition worsened progressively and he finally died 10 days after his admittance to hospital. The autopsy could be performed. The Papanicolaou-stained cytospin smears of the cerebrospinal fluid (CSF) showed tumor cells with enlarged nuclei and abundant vacuolated cytoplasms (Figure 1A). Numerous mononuclear cells and basophilic amorphous material were in the background. The vacuolated cells were also positive for the PAS stain. ... CT scans revealed a sinonasal tumor of an apparent ethmoidal origin (Figure 1B).
Source: QJM
DOI: 10.1093/qjmed/hcv004
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2069065154